Nicotine can worsen depression or anxiety symptoms. Nicotine is in cigarettes and most vape products.
Bi-directional associations of electronic and combustible cigarette use onset patterns with depressive symptoms in adolescents. William V. Lechner,a,* Tim Janssen,a Christopher W. Kahler,a Janet Audrain-McGovern,b and Adam M. Leventhalc
Nicotine Modulation of Fear Memories and Anxiety: Implications for Learning and Anxiety Disorders. Munir Gunes Kutlu, Ph.D. and Thomas J. Gould, Ph.D. Temple University, Weiss Hall, Philadelphia, PA 19122, USA