Nicotine can worsen depression or anxiety symptoms. Nicotine is in cigarettes and most vape products.

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Source 1:

Bi-directional associations of electronic and combustible cigarette use onset patterns with depressive symptoms in adolescents. William V. Lechner,a,* Tim Janssen,a Christopher W. Kahler,a Janet Audrain-McGovern,b and Adam M. Leventhalc


Source 2:

Nicotine Modulation of Fear Memories and Anxiety: Implications for Learning and Anxiety Disorders. Munir Gunes Kutlu, Ph.D. and Thomas J. Gould, Ph.D. Temple University, Weiss Hall, Philadelphia, PA 19122, USA


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