Cancer

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Because of the tobacco industry's products, about 353 people in the U.S. die of lung cancer every day.

Source: "Tobacco Use. Targeting The Nations Leading Killer: At A Glance 2010." Centers for Disease Control and Prevention, National Center for Chronic Disease Prevention and Health Promotion. Atlanta, GA: 2. Web.
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Of current smokers in the U.S., 358,000 have a cancer other than lung cancer from smoking.

Source: Cigarette Smoking Attributable Morbidity - United States, 2000. CDC. 04 Sept. 2003; 52(35) 842-844. Table.
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In a file from 1978, Big Tobacco described cancer as "an essential ingredient of life." Wait, they're talking about cancer, right?

Source: "A Public Relations Strategy for the Tobacco Advisory Council Appraisal & Proposals Prepared by Campbell-Johnson Ltd." Truth Tobacco Industry Documents. 20 Nov. 1978. Report.
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In 1997, one tobacco company CEO said he would probably "instantly" shut his doors "to get a better hold on things" if it were proved to his satisfaction that smoking causes cancer. That same company now admits on their website that smoking causes cancer, but they're still open for business.

Source: "In the Fifteenth Judicial Circuit Court in and for Palm Beach County, Florida Case No. CL 95-1466 AH The State of Florida, et al., Plaintiff, Vs. The American Tobacco Company, et al., Defendants. Deposition of Geoffrey C. Bible Taken at the Instance of Plaintiffs." Truth Tobacco Industry Documents. 21 Aug. 1997. Deposition.
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The most common causes of death among people with mental illness are heart disease, cancer, and lung disease, which can all be caused by smoking.

Source: Tobacco Use Among Adults with Mental Illness and Substance Use Disorders (Secondary Source CDC Report)
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In the U.S., 160,000 people die each year from smoking-related lung cancer.

Source: U.S. Department of Health and Human Services. The Health Consequences of Smoking: 50 Years of Progress. A Report of the Surgeon General. Atlanta, GA: U.S. Department of Health and Human Services, Centers for Disease Control and Prevention, National Center for Chronic Disease Prevention and Health Promotion, Office on Smoking and Health, 2014.
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Radioactive Polonium-210 is found in cigarette smoke. Polonium-210 contributes to cancer.

Source: "Smoking and Tobacco Control." U.S. Department of Health and Human Services, Public Health Service, National Institutes of Health, National Cancer Institute. Risks Associated with Smoking Cigarettes with Low Machine-Measured Yields of Tar and Nicotine. 19 Nov. 2001: 180.
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Cigarette smokers are 20 times more likely to develop lung cancer than non-smokers.

Source: "The Health Consequences of Smoking—50 Years of Progress. Surgeon General's Report." U.S. Department of Health and Human Services, Centers for Disease Control and Prevention, National Center for Chronic Disease Prevention and Health Promotion, Office on Smoking and Health. Cancer, 2014: 9. Report.
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Hookah smoke has been associated with oral, lung and bladder cancer, not to mention clogged arteries and heart disease.

Source: Cobb, Caroline, et al."Waterpipe Tobacco Smoking: An Emerging Health Crisis in the United States." American Journal of Health Behavior. 34(3). May-June 2010: 275–285. Web.
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Benzene is in tobacco smoke. Benzene causes cancer.

Source: "Smoking and Tobacco Control." U.S. Department of Health and Human Services, Public Health Service, National Institutes of Health, National Cancer Institute. Bethesda, MD. Risks Associated with Smoking Cigarettes with Low Machine-Measured Yields of Tar and Nicotine. 19 Nov. 2001: 176.
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69 animal and/or human carcinogens are in tobacco smoke.

Source: "Smoking and Tobacco Control." U.S. Department of Health and Human Services, Public Health Service, National Institutes of Health, National Cancer Institute. Bethesda, MD. Risks Associated with Smoking Cigarettes with Low Machine-Measured Yields of Tar and Nicotine. 19 Nov. 2001.
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Smokeless tobacco use causes oral cancer, lesions, and gum recession.

Source: Nelson, D.E., et al. "Trends in Smokeless Tobacco Use Among Adults and Adolescents in the United States." American Journal of Public Health. 96(5). May 2006: 897–905.
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