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NOTHIN' BUT THE COLD, HARD TRUTH.

More than two-thirds of people admitted into substance abuse treatment programs first used a non-heroin opioid by age 25.

Source: Substance Abuse and Mental Health Services Administration, Center for Behavioral Health Statistics and Quality. Treatment Episode Data Set (TEDS): 2003-2013. National Admissions to Substance Abuse Treatment Services. Rockville, MD: Substance Abuse and Mental Health Services Administration, 2015.
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In 2013, the United States, which continued to be the principal consumer country of oxycodone, accounted for 78 percent of the world total.

Source: United Nations: International Narcotics Control Board. Report of the International Narcotics Control Board for 2014. Accessed June 2018.
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In 2011, more than 420,000 emergency department visits were related to the misuse or abuse of narcotic pain relievers.

Source: Substance Abuse and Mental Health Services Administration, Drug Abuse Warning Network, 2011: National Estimates of Drug-Related Emergency Department Visits. Rockville, MD: Substance Abuse and Mental Health Services Administration; 2013.
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According to the CDC, healthcare providers wrote 259M prescriptions for opioid pain relievers in 2012, which is enough for every adult in America to fill one prescription.

Source: Paulozzi LJ, Mack KA, Hockenberry JM. Vital signs: variation among states in prescribing of opioid pain relievers and benzodiazepines—United States, 2012. MMWR Morb Mortal Wkly Rep 2014;63:563–8.
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80% of heroin users started with a prescription painkiller.

Source: Jones CM. Heroin use and heroin use risk behaviors among nonmedical users of prescription opioid pain relievers – United States, 2002-2004 and 2008-2010. Drug Alcohol Depend (2013) 132:95–100
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Opioids can cause constipation.

Source: Lee, A.A. & Hasler, W.L. Curr Treat Options Gastro (2016) 14: 478.
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Dependence on prescription opioids can happen after just five days.

Source: Shah A, Hayes CJ, Martin BC. Characteristics of Initial Prescription Episodes and Likelihood of Long-Term Opioid Use — United States, 2006–2015. MMWR Morb Mortal Wkly Rep 2017;66:265–269. DOI: http://dx.doi.org/10.15585/mmwr.mm6610a1
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In 2010, for every woman that died of a prescription painkiller overdose, 30 went to the ER for misuse or abuse.

Source: Centers for Disease Control and Prevention. Vital Signs: Overdoses of Prescription Opioid Pain Relievers and Other Drugs Among Women — United States, 1999–2010. MMWR 2013;62:537-542.
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Heroin-related overdose deaths increased 5x from 2010 to 2017.

Source: Scholl L, Seth P, Kariisa M, Wilson N, Baldwin G. Drug and Opioid-Involved Overdose Deaths — United States, 2013–2017. MMWR Morb Mortal Wkly Rep 2019;67:1419–1427. DOI: http://dx.doi.org/10.15585/mmwr.mm675152e1.
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Non-addictive painkillers, like ibuprofen and acetaminophen, can be just as effective as prescription opioids at reducing certain types of pain.

Source: Chang AK, Bijur PE, Esses D, Barnaby DP, Baer J. Effect of a Single Dose of Oral Opioid and Nonopioid Analgesics on Acute Extremity Pain in the Emergency DepartmentA Randomized Clinical Trial. JAMA.2017;318(17):1661–1667. doi:10.1001/jama.2017.16190
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In 2017, 70% of overdose deaths in D.C. involved fentanyl or its analogues.

Source: Leak C. Opioid-related Fatal Overdoses: January 1, 2014 to December 31, 2017. Government of the District of Columbia Office of the Chief Medical Examiner. 2018.
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In 2012, every 25 minutes, a baby was born suffering from opioid withdrawal.

Source: Patrick SW, Davis MM, Lehmann CU, Cooper WO. Increasing incidence and geographic distribution of neonatal abstinence syndrome: United States 2009 to 2012 [published correction appears in J Perinatol. 2015 Aug;35(8):667. Lehman, C U [corrected to Lehmann, C U]]. J Perinatol. 2015;35(8):650–655. doi:10.1038/jp.2015.36
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