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In 2010, every 3 minutes, a woman went to the ER for prescription painkiller misuse.

Source: Centers for Disease Control and Prevention. Vital Signs: Overdoses of Prescription Opioid Pain Relievers and Other Drugs Among Women — United States, 1999–2010. MMWR 2013;62:537-542.
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A 2020 study published by researchers at UCSF found that JUUL delivers five times more nicotine to the blood, per puff, than a Marlboro.

Source: Maier, Scott. "JUUL Delivers Substantially More Nicotine than Previous Generation E-Cigs and Cigarettes." USCF News. 6 January. 2020. Article.
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In 2017, 10.3 million young adults used a prescription opioid.

Source: Center for Behavioral Health Statistics and Quality. (2018). 2017 National Survey on Drug Use and Health: Detailed Tables. Substance Abuse and Mental Health Services Administration, Rockville, MD.
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JUUL (or pod-based e-cigs) can deliver more nicotine than a cigarette.

Source: Stella Juhyun Lee, PhD1; Vaughan W. Rees, PhD2; Noam Yossefy, MPH2; et al. (2020, June 1). Youth and Young Adult Use of Pod-Based Electronic Cigarettes From 2015 to 2019. Retrieved from https://jamanetwork.com/journals/jamapediatrics/article-abstract/2766303.
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There were 1.68 million potential years of life lost to opioids in the United States in 2016.

Source: Gomes T, Tadrous M, Mamdani MM, Paterson JM, Juurlink DN. The Burden of Opioid-Related Mortality in the United States. JAMA Netw Open. 2018;1(2):e180217. doi:10.1001/jamanetworkopen.2018.0217
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In 2013, the United States, which continued to be the principal consumer country of oxycodone, accounted for 78 percent of the world total.

Source: United Nations: International Narcotics Control Board. Report of the International Narcotics Control Board for 2014. Accessed June 2018.
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The number of women who used opioids during pregnancy increased nearly 70% between 2015 and 2017.

Source: Center for Behavioral Health Statistics and Quality. (2018). 2017 National Survey on Drug Use and Health: Detailed Tables. Substance Abuse and Mental Health Services Administration, Rockville, MD
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Heroin-related overdose deaths increased 5x from 2010 to 2017.

Source: Scholl L, Seth P, Kariisa M, Wilson N, Baldwin G. Drug and Opioid-Involved Overdose Deaths — United States, 2013–2017. MMWR Morb Mortal Wkly Rep 2019;67:1419–1427. DOI: http://dx.doi.org/10.15585/mmwr.mm675152e1.
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Non-addictive painkillers, like ibuprofen and acetaminophen, can be just as effective as prescription opioids at reducing certain types of pain.

Source: Chang AK, Bijur PE, Esses D, Barnaby DP, Baer J. Effect of a Single Dose of Oral Opioid and Nonopioid Analgesics on Acute Extremity Pain in the Emergency DepartmentA Randomized Clinical Trial. JAMA.2017;318(17):1661–1667. doi:10.1001/jama.2017.16190
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An American Heart Association study finds that e-cigarettes may not be any better than cigarettes for cardiovascular health & researchers found that vaping and smoking can cause a similar level of damage to the arteries.

Source: Journal of the American Heart Association Report. "E-cigarette Users Experience Vascular Damage Siimilar to that of Smokers of Combustible Cigarettes." Mirror Co UK. 29 April. 2020. Press Release.
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According to the CDC, healthcare providers wrote 259M prescriptions for opioid pain relievers in 2012, which is enough for every adult in America to fill one prescription.

Source: Paulozzi LJ, Mack KA, Hockenberry JM. Vital signs: variation among states in prescribing of opioid pain relievers and benzodiazepines—United States, 2012. MMWR Morb Mortal Wkly Rep 2014;63:563–8.
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