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As the death rate of major killers like cancer and heart disease decline, opioid death rates continue to rise.

Source: National Center for Health Statistics. Health, United States, 2014: With Special Feature on Adults Aged 55-64. Hyattsville, MD. 2015. https://www.cdc.gov/nchs/data/hus/hus14.pdf. Accessed June 2018.
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In 2017, two out of three drug overdose deaths involved some type of opioid.

Source: Scholl L, Seth P, Kariisa M, Wilson N, Baldwin G. Drug and Opioid-Involved Overdose Deaths — United States, 2013–2017. MMWR Morb Mortal Wkly Rep 2019;67:1419–1427. DOI: http://dx.doi.org/10.15585/mmwr.mm675152e1.
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In 2010, for every woman that died of a prescription painkiller overdose, 30 went to the ER for misuse or abuse.

Source: Centers for Disease Control and Prevention. Vital Signs: Overdoses of Prescription Opioid Pain Relievers and Other Drugs Among Women — United States, 1999–2010. MMWR 2013;62:537-542.
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In 2016, 1 in 5 deaths among young adults were opioid related.

Source: Gomes T, Tadrous M, Mamdani MM, Paterson J, Juurlink DN. The burden of opioid-related mortality in the united states. JAMA Network Open. 2018;1(2):e180217.
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80% of heroin users started with a prescription painkiller.

Source: Jones CM. Heroin use and heroin use risk behaviors among nonmedical users of prescription opioid pain relievers – United States, 2002-2004 and 2008-2010. Drug Alcohol Depend (2013) 132:95–100
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Opioid painkillers like Vicodin® and OxyContin® are chemically similar to heroin.

Source: NIDA. Opioids. National Institute on Drug Abuse website. https://www.drugabuse.gov/drugs-abuse/opioids. . Accessed May 11, 2018.
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Every day in 2017, an estimated 1,300 young adults misused an opioid prescription for the first time.

Source: Substance Abuse and Mental Health Services Administration. (2018). Key substance use and mental health indicators in the United States: Results from the 2017 National Survey on Drug Use and Health (HHS Publication No. SMA 18-5068, NSDUH Series H-53). Rockville, MD: Center for Behavioral Health Statistics and Quality, Substance Abuse and Mental Health Services Administration.
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In 2012, every 25 minutes, a baby was born suffering from opioid withdrawal.

Source: Patrick SW, Davis MM, Lehmann CU, Cooper WO. Increasing incidence and geographic distribution of neonatal abstinence syndrome: United States 2009 to 2012 [published correction appears in J Perinatol. 2015 Aug;35(8):667. Lehman, C U [corrected to Lehmann, C U]]. J Perinatol. 2015;35(8):650–655. doi:10.1038/jp.2015.36
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Smokers are more likely to be opioid abusers than non-smokers.

Source: Zale EL, Dorfman ML, Hooten WM, Warner DO, Zvolensky MJ, Ditre JW. Tobacco Smoking, Nicotine Dependence, and Patterns of Prescription Opioid Misuse: Results From a Nationally Representative Sample. Nicotine Tob Res. 2014;17(9):1096-103.
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Since 1999, over 9,000 children and teens have died from opioid overdoses.

Source: Centers for Disease Control and Prevention. CDC WONDER: Multiple Cause of Death 1999-2017.
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Individuals who are prescribed opioids prior to graduating high school are 33% more likely to misuse prescription opioids after graduating.

Source: Prescription Opioids in Adolescence and Future Opioid Misuse Richard Miech, Lloyd Johnston, Patrick M. O’Malley, Katherine M. Keyes, Kennon Heard Pediatrics Nov 2015, 136 (5) e1169-e1177; DOI: 10.1542/peds.2015-1364
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Opioids can cause constipation.

Source: Lee, A.A. & Hasler, W.L. Curr Treat Options Gastro (2016) 14: 478.
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