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Non-addictive painkillers, like ibuprofen and acetaminophen, can be just as effective as prescription opioids at reducing certain types of pain.

Source: Chang AK, Bijur PE, Esses D, Barnaby DP, Baer J. Effect of a Single Dose of Oral Opioid and Nonopioid Analgesics on Acute Extremity Pain in the Emergency DepartmentA Randomized Clinical Trial. JAMA.2017;318(17):1661–1667. doi:10.1001/jama.2017.16190
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No one knows the long-term effects of JUULing.

Source: Angelicalavito. (2019, July 13). As Juul grapples with teen vaping 'epidemic,' CEO tells parents 'I'm sorry'. Retrieved from https://www.cnbc.com/2019/07/13/as-juul-deals-with-teen-vaping-epidemic-ceo-tells-parents-im-sorry.html
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Opioid overdose deaths increased almost 6x from 1999 to 2017.

Source: Scholl L, Seth P, Kariisa M, Wilson N, Baldwin G. Drug and Opioid-Involved Overdose Deaths — United States, 2013–2017. MMWR Morb Mortal Wkly Rep 2019;67:1419–1427. DOI: http://dx.doi.org/10.15585/mmwr.mm675152e1.
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In 2010, every 3 minutes, a woman went to the ER for prescription painkiller misuse.

Source: Centers for Disease Control and Prevention. Vital Signs: Overdoses of Prescription Opioid Pain Relievers and Other Drugs Among Women — United States, 1999–2010. MMWR 2013;62:537-542.
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There were 1.68 million potential years of life lost to opioids in the United States in 2016.

Source: Gomes T, Tadrous M, Mamdani MM, Paterson JM, Juurlink DN. The Burden of Opioid-Related Mortality in the United States. JAMA Netw Open. 2018;1(2):e180217. doi:10.1001/jamanetworkopen.2018.0217
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Opioids can cause constipation.

Source: Lee, A.A. & Hasler, W.L. Curr Treat Options Gastro (2016) 14: 478.
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In 2013, the United States, which continued to be the principal consumer country of oxycodone, accounted for 78 percent of the world total.

Source: United Nations: International Narcotics Control Board. Report of the International Narcotics Control Board for 2014. Accessed June 2018.
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As the death rate of major killers like cancer and heart disease decline, opioid death rates continue to rise.

Source: National Center for Health Statistics. Health, United States, 2014: With Special Feature on Adults Aged 55-64. Hyattsville, MD. 2015. https://www.cdc.gov/nchs/data/hus/hus14.pdf. Accessed June 2018.
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In 2010, for every woman that died of a prescription painkiller overdose, 30 went to the ER for misuse or abuse.

Source: Centers for Disease Control and Prevention. Vital Signs: Overdoses of Prescription Opioid Pain Relievers and Other Drugs Among Women — United States, 1999–2010. MMWR 2013;62:537-542.
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In 2017, two out of three drug overdose deaths involved some type of opioid.

Source: Scholl L, Seth P, Kariisa M, Wilson N, Baldwin G. Drug and Opioid-Involved Overdose Deaths — United States, 2013–2017. MMWR Morb Mortal Wkly Rep 2019;67:1419–1427. DOI: http://dx.doi.org/10.15585/mmwr.mm675152e1.
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More than 17,000 people died from prescription opioid overdoses in 2017.

Source: Scholl L, Seth P, Kariisa M, Wilson N, Baldwin G. Drug and Opioid-Involved Overdose Deaths — United States, 2013–2017. MMWR Morb Mortal Wkly Rep 2019;67:1419–1427. DOI: http://dx.doi.org/10.15585/mmwr.mm675152e1
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In 2017, 70% of overdose deaths in D.C. involved fentanyl or its analogues.

Source: Leak C. Opioid-related Fatal Overdoses: January 1, 2014 to December 31, 2017. Government of the District of Columbia Office of the Chief Medical Examiner. 2018.
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