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Smokers are more likely to be opioid abusers than non-smokers.

Source: Zale EL, Dorfman ML, Hooten WM, Warner DO, Zvolensky MJ, Ditre JW. Tobacco Smoking, Nicotine Dependence, and Patterns of Prescription Opioid Misuse: Results From a Nationally Representative Sample. Nicotine Tob Res. 2014;17(9):1096-103.
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In 2017, two out of three drug overdose deaths involved some type of opioid.

Source: Scholl L, Seth P, Kariisa M, Wilson N, Baldwin G. Drug and Opioid-Involved Overdose Deaths — United States, 2013–2017. MMWR Morb Mortal Wkly Rep 2019;67:1419–1427. DOI: http://dx.doi.org/10.15585/mmwr.mm675152e1.
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Dependence on prescription opioids can happen after just five days.

Source: Shah A, Hayes CJ, Martin BC. Characteristics of Initial Prescription Episodes and Likelihood of Long-Term Opioid Use — United States, 2006–2015. MMWR Morb Mortal Wkly Rep 2017;66:265–269. DOI: http://dx.doi.org/10.15585/mmwr.mm6610a1
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Opioid overdose deaths increased almost 6x from 1999 to 2017.

Source: Scholl L, Seth P, Kariisa M, Wilson N, Baldwin G. Drug and Opioid-Involved Overdose Deaths — United States, 2013–2017. MMWR Morb Mortal Wkly Rep 2019;67:1419–1427. DOI: http://dx.doi.org/10.15585/mmwr.mm675152e1.
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Every day, 130 Americans die after overdosing on opioids.

Source: Hedegaard H, Miniño AM, Warner M. Drug overdose deaths in the United States, 1999–2017. NCHS Data Brief, no 329. Hyattsville, MD: National Center for Health Statistics. 2018.
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The number of women who used opioids during pregnancy increased nearly 70% between 2015 and 2017.

Source: Center for Behavioral Health Statistics and Quality. (2018). 2017 National Survey on Drug Use and Health: Detailed Tables. Substance Abuse and Mental Health Services Administration, Rockville, MD
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As the death rate of major killers like cancer and heart disease decline, opioid death rates continue to rise.

Source: National Center for Health Statistics. Health, United States, 2014: With Special Feature on Adults Aged 55-64. Hyattsville, MD. 2015. https://www.cdc.gov/nchs/data/hus/hus14.pdf. Accessed June 2018.
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In 2016, enough painkillers were prescribed to medicate every American adult 30 mg of hydrocodone every day for almost a month.

Source: Guy GP Jr., Zhang K, Bohm MK, et al. Vital Signs: Changes in Opioid Prescribing in the United States, 2006–2015. MMWR Morb Mortal Wkly Rep 2017;66:697–704. DOI: http://dx.doi.org/10.15585/mmwr.mm6626a4
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In 2017, 70% of overdose deaths in D.C. involved fentanyl or its analogues.

Source: Leak C. Opioid-related Fatal Overdoses: January 1, 2014 to December 31, 2017. Government of the District of Columbia Office of the Chief Medical Examiner. 2018.
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In 2012, every 25 minutes, a baby was born suffering from opioid withdrawal.

Source: Patrick SW, Davis MM, Lehmann CU, Cooper WO. Increasing incidence and geographic distribution of neonatal abstinence syndrome: United States 2009 to 2012 [published correction appears in J Perinatol. 2015 Aug;35(8):667. Lehman, C U [corrected to Lehmann, C U]]. J Perinatol. 2015;35(8):650–655. doi:10.1038/jp.2015.36
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Individuals who are prescribed opioids prior to graduating high school are 33% more likely to misuse prescription opioids after graduating.

Source: Prescription Opioids in Adolescence and Future Opioid Misuse Richard Miech, Lloyd Johnston, Patrick M. O’Malley, Katherine M. Keyes, Kennon Heard Pediatrics Nov 2015, 136 (5) e1169-e1177; DOI: 10.1542/peds.2015-1364
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The average days’ supply of opioids prescribed by doctors in the U.S. increased 33% from 2006 to 2015.

Source: Guy GP Jr., Zhang K, Bohm MK, et al. Vital Signs: Changes in Opioid Prescribing in the United States, 2006–2015. MMWR Morb Mortal Wkly Rep 2017;66:697–704. DOI: http://dx.doi.org/10.15585/mmwr.mm6626a4
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