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In 2017, two out of three drug overdose deaths involved some type of opioid.

Source: Scholl L, Seth P, Kariisa M, Wilson N, Baldwin G. Drug and Opioid-Involved Overdose Deaths — United States, 2013–2017. MMWR Morb Mortal Wkly Rep 2019;67:1419–1427. DOI: http://dx.doi.org/10.15585/mmwr.mm675152e1.
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In 2013, the United States, which continued to be the principal consumer country of oxycodone, accounted for 78 percent of the world total.

Source: United Nations: International Narcotics Control Board. Report of the International Narcotics Control Board for 2014. Accessed June 2018.
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Every day, 130 Americans die after overdosing on opioids.

Source: Hedegaard H, Miniño AM, Warner M. Drug overdose deaths in the United States, 1999–2017. NCHS Data Brief, no 329. Hyattsville, MD: National Center for Health Statistics. 2018.
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As the death rate of major killers like cancer and heart disease decline, opioid death rates continue to rise.

Source: National Center for Health Statistics. Health, United States, 2014: With Special Feature on Adults Aged 55-64. Hyattsville, MD. 2015. https://www.cdc.gov/nchs/data/hus/hus14.pdf. Accessed June 2018.
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Smokers are more likely to be opioid abusers than non-smokers.

Source: Zale EL, Dorfman ML, Hooten WM, Warner DO, Zvolensky MJ, Ditre JW. Tobacco Smoking, Nicotine Dependence, and Patterns of Prescription Opioid Misuse: Results From a Nationally Representative Sample. Nicotine Tob Res. 2014;17(9):1096-103.
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According to the CDC, healthcare providers wrote 259M prescriptions for opioid pain relievers in 2012, which is enough for every adult in America to fill one prescription.

Source: Paulozzi LJ, Mack KA, Hockenberry JM. Vital signs: variation among states in prescribing of opioid pain relievers and benzodiazepines—United States, 2012. MMWR Morb Mortal Wkly Rep 2014;63:563–8.
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More than two-thirds of people admitted into substance abuse treatment programs first used a non-heroin opioid by age 25.

Source: Substance Abuse and Mental Health Services Administration, Center for Behavioral Health Statistics and Quality. Treatment Episode Data Set (TEDS): 2003-2013. National Admissions to Substance Abuse Treatment Services. Rockville, MD: Substance Abuse and Mental Health Services Administration, 2015.
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In 2011, more than 420,000 emergency department visits were related to the misuse or abuse of narcotic pain relievers.

Source: Substance Abuse and Mental Health Services Administration, Drug Abuse Warning Network, 2011: National Estimates of Drug-Related Emergency Department Visits. Rockville, MD: Substance Abuse and Mental Health Services Administration; 2013.
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Adolescent athletes in some high-injury sports are at a 50% higher risk of misusing prescription painkillers than their peers who don't participate in these sports.

Source: Veliz PT, Boyd C, McCabe SE. Playing through pain: sports participation and nonmedical use of opioid medications among adolescents. Am J Public Health. 2013;103(5):e28–e30. doi:10.2105/AJPH.2013.301242
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The number of women who used opioids during pregnancy increased nearly 70% between 2015 and 2017.

Source: Center for Behavioral Health Statistics and Quality. (2018). 2017 National Survey on Drug Use and Health: Detailed Tables. Substance Abuse and Mental Health Services Administration, Rockville, MD
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Over half of young adults who misused prescription opioids got them from a friend or family member.

Source: Center for Behavioral Health Statistics and Quality. (2017). 2016 National Survey on Drug Use and Health: Detailed Tables. Substance Abuse and Mental Health Services Administration, Rockville, MD.
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Opioids can cause constipation.

Source: Lee, A.A. & Hasler, W.L. Curr Treat Options Gastro (2016) 14: 478.
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