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80% of heroin users started with a prescription painkiller.

Source: Jones CM. Heroin use and heroin use risk behaviors among nonmedical users of prescription opioid pain relievers – United States, 2002-2004 and 2008-2010. Drug Alcohol Depend (2013) 132:95–100
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Dependence on prescription opioids can happen after just five days.

Source: Shah A, Hayes CJ, Martin BC. Characteristics of Initial Prescription Episodes and Likelihood of Long-Term Opioid Use — United States, 2006–2015. MMWR Morb Mortal Wkly Rep 2017;66:265–269. DOI: http://dx.doi.org/10.15585/mmwr.mm6610a1
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The average days’ supply of opioids prescribed by doctors in the U.S. increased 33% from 2006 to 2015.

Source: Guy GP Jr., Zhang K, Bohm MK, et al. Vital Signs: Changes in Opioid Prescribing in the United States, 2006–2015. MMWR Morb Mortal Wkly Rep 2017;66:697–704. DOI: http://dx.doi.org/10.15585/mmwr.mm6626a4
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Every 11 minutes someone in America dies from an opioid overdose.

Source: Hedegaard H, Miniño AM, Warner M. Drug overdose deaths in the United States, 1999–2017. NCHS Data Brief, no 329. Hyattsville, MD: National Center for Health Statistics. 2018.
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68% of the people who died from opioid overdoses in 2017 were men.

Source: Centers for Disease Control and Prevention, National Center for Health Statistics. Multiple Cause of Death 1999-2017 on CDC WONDER Online Database, released December, 2018. Data are from the Multiple Cause of Death Files, 1999-2017, as compiled from data provided by the 57 vital statistics jurisdictions through the Vital Statistics Cooperative Program.
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The opioid mortality rate increased as the U.S. life expectancy rate decreased.

Source: Xu JQ, Murphy SL, Kochanek KD, Bastian B,Arias E. Deaths: Final data for 2016. National Vital Statistics Reports; vol 67 no 5. Hyattsville, MD: National Center for Health Statistics. 2018.
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Individuals who are prescribed opioids prior to graduating high school are 33% more likely to misuse prescription opioids after graduating.

Source: Prescription Opioids in Adolescence and Future Opioid Misuse Richard Miech, Lloyd Johnston, Patrick M. O’Malley, Katherine M. Keyes, Kennon Heard Pediatrics Nov 2015, 136 (5) e1169-e1177; DOI: 10.1542/peds.2015-1364
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103,000 adolescents had an opioid use disorder in 2017.

Source: Substance Abuse and Mental Health Services Administration. (2018). Key substance use and mental health indicators in the United States: Results from the 2017 National Survey on Drug Use and Health (HHS Publication No. SMA 18-5068, NSDUH Series H-53). Rockville, MD: Center for Behavioral Health Statistics and Quality, Substance Abuse and Mental Health Services Administration.
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More than two-thirds of people admitted into substance abuse treatment programs first used a non-heroin opioid by age 25.

Source: Substance Abuse and Mental Health Services Administration, Center for Behavioral Health Statistics and Quality. Treatment Episode Data Set (TEDS): 2003-2013. National Admissions to Substance Abuse Treatment Services. Rockville, MD: Substance Abuse and Mental Health Services Administration, 2015.
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In 2017, 47,600 people died of opioid overdoses in America.

Source: Hedegaard H, Miniño AM, Warner M. Drug overdose deaths in the United States, 1999–2017. NCHS Data Brief, no 329. Hyattsville, MD: National Center for Health Statistics. 2018.
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The number of women who used opioids during pregnancy increased nearly 70% between 2015 and 2017.

Source: Center for Behavioral Health Statistics and Quality. (2018). 2017 National Survey on Drug Use and Health: Detailed Tables. Substance Abuse and Mental Health Services Administration, Rockville, MD
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In 2011, more than 420,000 emergency department visits were related to the misuse or abuse of narcotic pain relievers.

Source: Substance Abuse and Mental Health Services Administration, Drug Abuse Warning Network, 2011: National Estimates of Drug-Related Emergency Department Visits. Rockville, MD: Substance Abuse and Mental Health Services Administration; 2013.
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